So you’re training hard, you’re eating right, taking your
supplements and you wonder, well why would my body want to make more estrogen,
if it doesn’t need more estrogen? The body is more complex than can ever be
explained in this write up. For instance, training with heavy weight increases
testosterone output, but it also increases cortisol which is one of your body’s
self-made anti-inflammatory compounds. Cortisol also releases fat for energy
during times of stress (more on this later). Cortisol is produced in pulses, so
under high physical or mental stress situation your body will purse or “surge”
its cortisol levels. What does this have to do with estrogen and E2-X™?
Cortisol surges increase abdominal fat storage. So the more body fat you have,
the more estrogen you have because the more fat you have, the more aromatase
enzymes you have. I have always had a theory of why very large and strong
powerlifters and strongmen/women tend to be “husky.” It’s like for most people
the heavier you lift, the “bigger” you get all around. Heavy lifting, training
hard and overtraining will increase cortisol production, which increases fat
stores, which increase aromatase enzyme levels. The use of pro-steroids,
testosterone, and even herbal test booster will increase estrogen. Some test
boosters like GET DIESEL’s DIESEL TEST Hardcore and DIESEL TEST Pro-cycle
contain DIM (a broccoli enzyme found in E2-X™),
but as you will learn later, DIM helps reduce bad estrogen, influencing the
production of beneficial estrogen. The special part about this is DIM doesn’t
stop estrogen from being produced; it helps prevent excess bad estrogen.
Reducing
bad estrogen can only take you so far. To eradicate high estrogen, you have to
block estrogen from being made in the first place. You have to go after the
aromatase enzyme. This is where E2-X™ comes in. E2-X works in two phases.
E2-X™ Phase 1 – Block Aromatase
The first phase is designed to stop estrogen formation by
blocking the aromatase enzyme (responsible for converting testosterone into
estrogen). This phase uses Acacetin (5,7-dihydroxy-4'-methoxyflavone); a
natural anti-aromatase enzyme found in the Damiana plant which has been long
used for its libido boosting properties by women.
Look at it this way. If you are trying to stop in from
raining an anti-aromatase would prevent clouds from forming all together. I
don’t want to say “prevent” because even the strongest anti-aromatase drugs
such as Femara (letrozole) and Arimidex (anastrozole) will not completely
prevent all estrogen formation, and nor do not want it to. Estrogen is needed
for many functions in the female body, but in the male body, beneficial
estrogen (2-hydroxy) have been shown to decrease body fat in mice (I have to
find this study) amongst other things. Estrogen also plays a role in libido
(sex drive) and is a large contributor to weight gain. Yes too low estrogen
equals weight gain…too high estrogen equals weight gain. Estrogen is also needed for strong bones. In
a study in the UK, 400 men with test levels under 300 ng/dl (nanograms per
deciliter) were either given synthetic testosterone, or synthetic testosterone AND an anti-aromatase drug. The group
that received the testosterone and the anti-aromatase showed significantly
higher reductions in body fat, significantly less erectile dysfunction and
higher sex drive (1).
Back to Acacetin. This naturally occurring compound is one
of over 20 enzymes in the Damiana plant that has anti-aromatase activity. The
wonderful thing about Acacetin is of the 20 enzymes identified in a study, it
was the one that provided the highest anti-aromatase activity with no
estrogenic activity (2).
With
anti-aromatase enzymes you are potentially dealing with a risk and reward
system. They can block the
formation of estrogen but to the human body, structurally some are so similar
to estrogen, they can increase estrogen activity. It may be a little confusing
but it’s like a crooked cop. They can prevent crime, and they can also increase
crime. Often users of anti-aromatase
supplements notice increased estrogenic activity with high estrogen symptoms.
Acacetin is a potent anti-aromatase found in nature that has no estrogenic
activity. It will not block estrogen
formation (anti-aromatase) and then turn around and be used as estrogen by the
body as with most other natural compounds that show promise as an
anti-aromatase.
E2-X™ also contains Acacetin because for one it’s
been around and consumed for many years as Damiana was a popular female libido
booster in the 90’s. This isn’t some “grey area” compound discovered 2 weeks
ago that we are rushing to be first to market with. That’s one of the reasons
why GET DIESEL has not had an anti-estrogen product until now. We have been the industry leader in effective
herbal test boosters for over 10 years, but we have never made an anti-estrogen
product because we wanted it to contain a natural anti-aromatase enzyme WITH NO
estrogenic activity. In addition, Acacetin was show to be a promising aid in
fighting rheumatoid arthritis which means it can also benefit joints because of
its anti-inflammatory properties (3).
Phase
2 – Reduce “bad” Estrogen
The 2nd phase of the E2-X™
effectiveness is DIM (Diindolylmethane). DIM is made from Indole-3-Carbinol
which comes from broccoli. Indole-3-Carbinol has a very low absorption and
effective rate and is used often over DIM in supplements because it is at least
1/3 the cost of DIM. Most anti-aromatase products are only that. Formulated to
block estrogen formation, but as previously stated, your body will not allow
you to completely block estrogen formation, and what is produced can either be
16-hydroxy estrogens (bad estrogens) or good 2-hydroxy estrogens. DIM increased the production of 2-hydroxy
estrogens and reduced bad estrogen. E2-X™ is formulated to reduced
increased estrogen formation when test levels go up, or to reduce medium to
high estrogen, AND it is also formulated to increase the production of
beneficial 2-hydroxy estrogens.
No
other anti-estrogen product combines the effects of a potent anti-aromatase
such as Acacetin with a high amount (over 140mg per capsule) of highly
bioavailable DIM in one capsule.
Other products online will run $40+ for the anti-aromatase
product, then you have to spend another $35- $40 a month on a DIM product. GET DIESEL has been using DIM since 2005 in
DIESEL TEST and actually used it in a few runs of DIESEL FUEL (fat burner)
pre-2005. We know DIM, and we know how to enhance its bioavailability and what
is an effective dose of it.
If
you are over 35 years old, on test boosters or hormones, in PCT, or have body
fat over 8%, you can benefit from using E2-X™ (and you are a male). Athletes
that train at a high level or everyday people exposed to high levels of mental
or physical stress can benefit from E2-X™ because it helps to reduce the
increases in estrogen production caused by spikes in cortisol (stress hormone).
E2-X™ can also be consumed
by women after consulting a physician and proper test have been performed to
identify estrogen dominance.
The
Estrogen Problem
As stated earlier, estrogen is needed for joint and bone
health as well as libido (sex drive). Too much estrogen will cause a bloated
look, weight gain, water retention, higher body fat, and has been linked to
diabetes and high blood lipid levels. Even worse, estrogen is the primary fuel
source for tumors and cancer cells. Now
we are in no way promoting this as an anti-cancer supplement or drug, you just should be aware the higher your
estrogen levels, the more of a beneficial environment your body is for the
growth of cancer cells. With
increased testosterone, comes increased estrogen. If you are taking test shots or
increasing testosterone naturally by training hard or with supplements you will
produce more estrogen. It doesn’t have as much to do with aromatase as much as
it has to do with how aromatase works.
Think of aromatase as a car wash sitting in fat cells. The more cars that enter
and leave a car wash, the more dirty cars you have converted to clean ones. The
more cars (testosterone) that come in, the more estrogen will leave (clean
cars). Actually it’s more like a tornado
destroying houses in its path because you want a clean car. If a tornado
(aromatase) is going to destroy 1 square mile of area it doesn’t matter how
many homes (testosterone) is in the way, they all are probably getting
destroyed. More homes do not mean you need more tornados to destroy them.
The
Cortisol Relation
The higher you boost your testosterone levels by heavy and
or frequent weight training, the more you will produce cortisol. An increase in
cortisol (stress hormone/anti-inflammatory) alone or with higher test levels
will increase estrogen at an even faster rate than testosterone alone because
cortisol increases mid-section fat. Cortisol does this because it causes fat to
be released (triglycerides) in to the blood.
To reduce this “free circulating fat” (if not used as energy) your body
redeposits the circulating fat the easiest around the mid-section. Cortisol is
released in pulses. When you are stressed either at work, at home or during
training, cortisol is pulsed much like how adrenaline is released to help you
deal with the stress. Remember, the body’s favorite energy source is fat. Fat
gives you 2x the calories for energy over carbohydrates. If you train hard,
combined with less than ideal hours of sleep, added to everyday life stress, every
time your cortisol shoots up, you are probably producing more belly fat.
Remember aromatase lives in fat cells, especially
mid-section fat.
It’s almost like unless you have less than 5% body fat; your test boosting
stack should start with an anti-estrogen product like E2-X™
and build from there. Even if you use an effective test booster like DIESEL
TEST Hardcore, Procycle or Raw Test, you will produce more estrogen. Now DIESEL
TEST (both forms) contains DIM to help reduce the formation of bad estrogen,
but you still will produce more estrogen because they increase testosterone.
It’s not necessarily a good idea to add an anti-aromatase to a test booster (in
one product), because everyone does not need to be on an anti-aromatase at the
same dosage ratio to their test booster. With E2-X™
you can customize its use, or even use it between cycles of DIESEL TEST or Raw
Test as a bridge supplement. You also
may be in a situation where you want lower estrogen, not necessarily sky high
testosterone. If you think your hormone replacement therapy (HRT) or test
boosters are giving you great results, wait until you add E2-X™
to them!
Signs
of high estrogen levels
-
Difficulty losing body fat, especially in the mid-section
- Disproportional weight gain, as in all to your mid-section
- Lower back fat to proportional to upper back fat (tire)
- Low muscle definition at an “average” to low body fat
- You notice less muscle hardness than when you were younger
- Gynecomastia aka “man boobs” or “b**** tits”
- Reduced erectile frequency (4)
THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FDA. THIS
PRODUCT IS NOT INTENDED (AT ALL) TO PREVENT OR CURE ANY DISEASE.
(1) Alexander, B. (2013). Men need ‘female’ hormone for sex
drive, fat control: study. NBC News. Retrieved from:
http://www.nbcnews.com/health/mens-health/men-need-female-hormone-sex-drive-fat-control-study-f8C11132419
(2) J Ethnopharmacol. 2008 Dec 8;120(3):387-93. doi: 10.1016/j.jep.2008.09.016. Epub 2008 Sep
26.
(3) J Cell Mol Med. 2015 Aug;19(8):1910-1915. doi: 10.1111/jcmm.12564. Epub 2015
Apr 9.
(4) Int J Impot Res. 2003 Feb;15(1):38-43.
